Page 1 - Reviews - NaturesPlus, Super C Complex, Sustained Release, 180 Tablets - iHerb
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Customer Ratings & Reviews

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4.7
Based on 6,386 ratings
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7.0 stars Introduction & context: NaturesPlus Super C Complex, Sustained Release delivers 1,000 mg of vitamin C per tablet—a clinically relevant dose aligning with studies investigating immune function and collagen synthesis. The sustained-release format aims to prolong plasma ascorbate levels, theoretically minimizing urinary excretion. Priced at ~$0.17/tablet, it undergoes NSF third-party testing for purity. However, the proprietary blend obscures exact amounts of bioflavonoids and rose hips. Evidence summary: Two RCTs (n=20–26) show 1,000 mg/day vitamin C reduces cold duration by ~8% in active individuals—modest but consistent. No significant effects on general population immunity. Bioavailability comparisons (ascorbate AUC0-24h) favor liposomal forms over standard tablets, though this product lacks such enhancements. Formulation & quality analysis: Ascorbic acid is the sole active form—bioavailable but prone to degradation. The sustained-release matrix (likely hydroxypropyl methylcellulose) is standard but unproven for superior absorption. Trace contaminants (lead <1 ppm) meet safety thresholds but aren’t ideal for long-term use. Safety & interactions: Generally safe up to 2,000 mg/day; high doses may cause gastrointestinal upset. Caution for renal impairment or iron overload disorders. Minimal interactions, but ascorbate can enhance iron absorption. Value & practicality: Cost-effective for daily immune support. Sustained release may suit those preferring once-daily dosing, though immediate-release alternatives offer similar efficacy at lower prices. Overall verdict + score: Moderate support for immune resilience with practical dosing. Lacks cutting-edge bioavailability features; transparency issues with proprietary blend. Suitable for budget-conscious individuals prioritizing basic ascorbate supplementation. Who it's for: Active adults or those prone to colds seeking affordable immune maintenance. Not ideal for high-dose therapeutic use. I’d opt for liposomal vitamin C if bioavailability were a priority.